Search
Now showing items 1-10 of 142
Pain treatment after surgery : with special reference to patient-controlled analgesia, early extubation and the use of paracetamol
(2004-11-26)
The introduction of general anaesthesia eliminated pain during surgical
operations. After surgery, however, pain and postoperative nausea and
vomiting (PONV) have remained a persistent problem for many patients. The
need ...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Alzheimer´s disease-related amyloid precursor protein and presenlin genes : normal function and pathophysiology
(2004-10-08)
or sporadic types. A number of genes have mutations that cause the familial forms of AD. These include the amyloid precursor protein (APP) gene and the presenilin (PS) 1 and 2 genes. Also, inheritance of the apolipoprotein E epsilon4 allele confers...
The fate of primary aneuploid cells in early embryonic development and stem cells
(2005-09-02)
Chromosomal aberrations occurring during gametogenesis and early embryonic development play a significant role in infertility and fetal loss in humans. Germ cells that have an abnormal number of chromosomes (aneuploidy) ...
Negative regulation of growth hormone (GH) signaling
(2005-01-14)
by increased growth rate and exaggerated responsiveness of hepatic GH-regulated genes. The mechanism of SOCS2 action involves its binding to GHR through the tyrosines 487 and 595 and its association to Elongin BC, probably forming an ubiquitin ligase complex...
On neck load among helicopter pilots : effects of head worn equipment, whole body vibration and neck position
(2005-09-13)
rotation, 2-3 % of neck flexion, and 1.5-2.5 % of trunk inclination. The use of NVG increased muscle activity in upper neck by 0.5-1.5 % and in lower neck by about 0.5 %. Results with added counterweight were about the same as with NVG. Muscle activity...
Hairdressers : hand eczema, hair dyes and hand protection
(2006-10-06)
for assessment of dermal exposure to permanent hair dyes on hairdressers' hands was developed and validated. The validated hand rinse method was used during hair dyeing in hairdressing salons for assessment of the exposure to p-phenylenediamine (PPD), toluene-2...
Dose-response modeling : evaluation, application, and development of procedures for benchmark dose analysis in health risk assessment of chemical substances
(2005-09-09)
In this thesis, dose-response modeling and procedures for benchmark dose
(BMD) analysis in health risk assessment of chemical substances have been
investigated.
The BMD method has been proposed as an alternative ...
Characterization of cochlear degeneration in the inner ear of the German waltzing guinea pig : a morphological, cellular, and molecular study
(2006-11-03)
difficult to identify. The degree of sensory hair cells degeneration varied even among animals of the same age. Morphometric analysis of the spiral ganglion neuron profile density showed a significant reduction in the old (1-2 years of age) animals...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
revealed a right - left hand side symmetry. Cigarette smoking was significantly associated with the prevalence and severity of vertical bone defects (Studies II and III). The relative risk associated with current smoking was 2 to 3-fold increased...