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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Immunotherapy with the anti-EpCAM monoclonal antibody and cytokines in patients with colorectal cancer : a clinical and experimental study
(2005-11-18)
NK cells should be considered to MAbbased treatment regimens.
The addition of GM-CSF, alpha-interferon and 5-fluorouracil to anti-EpCAM mMAb seemed to improved the antitumor response rate compared to historical control patients treated with anti...
The fate of primary aneuploid cells in early embryonic development and stem cells
(2005-09-02)
Chromosomal aberrations occurring during gametogenesis and early embryonic development play a significant role in infertility and fetal loss in humans. Germ cells that have an abnormal number of chromosomes (aneuploidy) ...
Born too small or too early : effects on blood pressure, renal function and retinal vascularization in adulthood : experimental and clinical studies
(2004-11-12)
Background: Several epidemiological studies the past fifteen years have
suggested a connection between fetal growth retardation and later effects
on adult health, such as an increased arterial blood pressure and type ...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and ...
PET studies of the serotonin transporter in the human brain
(2006-10-27)
The serotonin (5-HT) system attracts considerable attention in research on the pathophysiology and drug treatment of neuropsychiatric disorders. The brain imaging technique Positron Emission Tomography (PET) allows for examination...
Learning to be a physiotherapist
(2006-05-12)
Few studies have explored student experience of learning in physiotherapy and none has explored student experience throughout an education programme from a student perspective. The traditional role of physiotherapists as ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
baseline in patients receiving IVIG, while the placebo group displayed a 5.8 % decrease ( p=0.029). Five of eight subscales of the SF 36 improved significantly over baseline in the IVIG group, but none in the placebo group. Two subscales, vitality...
On neck load among helicopter pilots : effects of head worn equipment, whole body vibration and neck position
(2005-09-13)
rotation, 2-3 % of neck flexion, and 1.5-2.5 % of trunk inclination. The use of NVG increased muscle activity in upper neck by 0.5-1.5 % and in lower neck by about 0.5 %. Results with added counterweight were about the same as with NVG. Muscle activity...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
-chloroacrylonitrile yielded, after expulsion of HCN by refluxing in ethanol, 1-benzyl-4,5,6,7-tetrahydroindole. Formylation and benzylimine formation followed by treatment with TosMIC furnished the desired 2-imidazolyltetrahydroindole....