Search
Now showing items 1-10 of 515
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
-PSOX, which mediates uptake of oxidized low-density lipoprotein (oxLDL) by cells. We detected abundant CXCL16/SR-PSOX and CXCR6 expression in atherosclerotic lesions from human subjects and apolipoprotein-Edeficient (ApoE-/-) mice. In monocytes, CXCL16/SR...
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(2006-09-15)
controls. The levels of plasma PRL were raised in 101 women with MG, but not in 91 men. There was an association between high prolactin levels and high levels of autoantibodies against the AChR. There was no association between PRL levels and thymic...
Modulation of the deubiquitnating system during lymphoid cell activation and viral infection
(2005-08-15)
-lymphocytes, as well as HPV E6/E7 immortalized keratinocytes. Both tumor specific and tissue specific patterns could be identified when profiling USP activity in a panel of tumor cell lines of different tissue origin. Only few USPs were active in primary cells...
Novel non-collagenous modulators of biomineralization in bone and dentin
(2004-11-26)
The formation of mineralized tissues such as bones and teeth is governed on many levels by molecular, genetic, and cellular events to culminate in terminally differentiated cells that secrete a specialized organic matrix, ...
Structure and function of the yeast mediator tail domain
(2005-12-30)
Mediator is a co-regulator complex that transduces regulatory information from activators and repressors to the RNA polymerase 11 transcription machinery. Mediator was originally discovered in Saccharomyces cerevisiae and ...
Cryo-electron tomography of individual protein molecules
(2005-08-29)
Averaging methods of determining structure, such as X-ray diffraction, do not preserve information about the flexibility of molecules. Cryo-electron tomography allows us to reconstruct individual hydrated objects. The ...
Sleepiness : night work, time zones and activity
(2006-05-26)
Shift work and travel across time zones affect sleep and alertness negatively, and hence influence accident rate. Self-selected work hours, contextual, and environmental factors affect sleepiness, but it is unclear exactly ...
Identification of tumor suppressor genes using the approach of gene inactivation test
(2006-05-26)
in one tested cancer cell line. However, all mutated genes and wild type PL6, RhoA, 3PK, BLU, 101F6, MLH1 and others didn't show this activity in the tested cell line(s), although they resided in frequently affected 3p21.3 regions. Some of the newly...
Apoptosis in myelodysplastic syndromes : effects of hemopoietic growth factors
(2004-09-03)
Increased apoptosis of hernatopoietic progenitors is a hallmark of myelodysplastic syndromes (MDS) and results in ineffective hematopoiesis. Erythroid apoptosis is thought to be the main mechanism underlying the severe ...
Women’s encounters with biomedical technology in the realm of cervical cancer screening
(2004-12-31)
As a form of biomedical technology, the Papanicolaou (Pap) smear has been described as the most widely used and established cane er- screening tool in the world. In Sweden, Pap smear technology triggered what is today an ...