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Host responses and bacterial virulence factors in Neisseria infections
(2004-08-27)
Neisseria meningitidis and Neisseria gonorrhoeae are human specific pathogens. N. meningitidis is a major cause of meningitis and sepsis, whilst N. gonorrhoeae causes many millions of cases of gonorrhea in the world every ...
Perlecan in vascular disease
(2005-01-28)
Atherosclerosis has become the most common cause of death in the world. The development of the disease involves accumulation of lipids in the inner layer of the vessel wall, the intima, and recruitment of inflammatory cells ...
Immunotherapy with the anti-EpCAM monoclonal antibody and cytokines in patients with colorectal cancer : a clinical and experimental study
(2005-11-18)
The tumor-associated antigen EpCAM (epithelial cell-adhesion molecule) (C017-1A) is over expressed by various human carcinomas, including colorectal carcinoma (CRC). This antigen can be used as a target structure for specific immunotherapy...
Coronary artery bypass surgery without extracorporeal circulation
(2006-03-10)
Introduction: Coronary artery bypass surgery with extracorporeal circulation is associated with a systemic inflammatory response syndrome that contributes to morbidity and mortality. Aortic cross clamping and cardioplegic ...
Bad breath : prevalence, periodontal disease, microflora and inflammatory markers
(2005-03-29)
Bad breath usually originates within the oral cavity and is believed to be associated with periodontal disease. The over all aim of the present thesis was to study periodontal conditions in subjects with bad breath as well ...
Non-conventional risk and prognostic factors in coronary heart disease : studies on heart rate variability, alcohol consumption, inflammation and depression
(2005-04-01)
not relate to any of the HRV parameters (paper I). Concentration of IL-6 showed an inverse relation to HRV even after adjustment for potential confounding factors (paper II). HRV parameters predicted all-cause and cardiovascular mortality in a 9-year follow...
Molecular studies of complications in end stage renal disease : focus on expression and variations of candidate susceptibility genes
(2005-09-09)
) and C-reactive protein (CRP) are highly elevated in ESRD patients and predict mortality in both healthy and uremic individuals. Hence putative SNPs that may regulate plasma levels of these proteins were investigated (IL-6 SNPs: -597G/A, -174G/C, 5014A...
Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease
(2006-11-10)
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased ...
Effects of gonadal hormone deficiency on bone mineral density : can physical activity increase bone mineral density in women?
(2006-08-11)
RH analogues for endometriosis for 6 months and hereby decreased estrogen levels led to a decrease in bone mineral density. Perimenopausal women with fluctuating estradiol levels and occasional ovulations were followed for 18 months. There was a significant...
Capsulotomy in anxiety disorders
(2006-05-26)
Background and aim: Anxiety disorders are common and a substantial proportion of patients do not respond to conventional treatments such as SSRIs or CBT. Capsulotomy is a neurosurgical treatment for treatment refractory ...