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Posttransplantational bone disease : the effect of immunosuppressive drugs on bone : clinical and experimental studies
(2002-11-14)
were repeated in 9 patients at 3 months, 6 months. and 12 months after liver transplantation (Paper 1). We found that an early and accentuated bone loss occurs during the first 6 months following transplantation, predominantly in sites enriched...
The effect of thrombin inhibitors on coagulation activity and generation of activated protein C
(2002-03-22)
The direct thrombin inhibitor inogatran was, in the TRIM trial (n=1209),
compared with unfractionated heparin (UFH) concerning the effect on
cardiovascular end-points in unstable coronary artery disease. The
results in ...
The loss of a husband to cancer : additional and avoidable psychological traumata
(2003-05-07)
of the prostate 1996 or of the urinary bladder 1995 or 1996, after a minimum disease duration of 3 months. All their surviving widows or partners (n=506) who were alive on the 1" of April 1999 and were 79 years or younger were contacted and compared to an age...
Clinical pharmacokinetics of intravenous ethanol : relationship between the ethanol space and total body water
(2001-10-26)
Introduction: Total body water (TBW) is an important parameter in
pathological states where the normal regulation of fluid balance is
impaired (e.g., during critical illness, congestive heart failure, bum
injury and ...
HMBG1 as a proinflammatory mediator in arthritis
(2003-05-02)
Proinflammatory cytokines are central in the pathogenesis of chronic arthritis and a new generation of therapeutics blocking TNF or IL-1 has improved outcome for many patients with inflammatory joint diseases. This thesis ...
Effects of influenza A virus infections and interferon-gamma on synapse formation and function in hippocampal neurons in culture
(2004-09-03)
The central nervous system (CNS) can be the target for several infections that include those with RNA viruses. The parenchyma of the CNS is considered an immuneprivileged site since it is protected behind the blood-brain ...
Novel neurophysiological monitors of the transition from wakefulness to loss of consciousness during anaesthesia
(2003-09-12)
Background: The concept of adequate anaesthesia is not easily defined. One important component of anaesthesia is the suppression of wakefulness, that is, a patient who does not experience sensory input such as hearing, ...
Digital intraoral radiography : determination of technical properties and application evaluations
(2002-05-03)
Digital registration of intraoral radiographs was introduced about 1990. One of the first systems on the market was the Sens-A-Ray (Regain Medical Systems AB, Sundsvall, Sweden). At the time of the introduction, it was ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
Malignant mesothelioma : an experimental study with emphasis on proteoglycans in mesothelial cell growth and differentiation
(2002-04-17)
Malignant mesothelioma is a highly aggressive tumor with median survival ranging from 4 to 12 months and, despite intense therapeutical efforts, it is invariably fatal. Mesothelioma cells are unique in the sense that they ...