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Mechanisms of immune escape : implications for immunotherapy against cancer
(2003-01-17)
doses of dietary vitamin E during a period of two weeks. In a majority of patients the supplementation of vitamin E lead to enhanced IL-2 and IFN-gamma production by their T cells. Moreover, CD4/CD8 ratios were increased after treatment with vitamin E...
The role of exercise and exercise-related factors in the control of mitochondrial oxidative function
(2002-05-10)
The effects of exercise and exercise-related factors on the control of
mitochondrial oxidative function were investigated in human and rat
skeletal muscle. Oxidative function was assessed through the measurement
of oxygen ...
Regulation of protein degradation by virus derived repeated amino acid sequences
(2002-05-14)
degradation was restored by deletion of the GAr, both in vitro and in vivo, whereas insertion of the GAr of various lengths and in different positions prevented the degradation of EBNA4 without considerable effect on ubiquitination. These results proposed...
Body site of cutaneous malignant melanoma : primary tumor location in relation to phenotypic and prognostic factors
(2002-11-08)
The main purpose of this thesis was to analyze the primary body site of cutaneous malignant melanoma (CMM) in relation to phenotypic traits and prognosis. It is clear that several characteristics of CMM are different, and ...
Circulating immune complexes in atherosclerotic vascular disease
(2001-08-31)
in those without CICs. Among men
homozygous for C4 null alleles, those who developed MI had higher
concentrations of CICs than did those who remained healthy.
In a five-year prospective study, CICs and antibodies against oxLDL were
associated...
Bile in the oesophagus contributes to the development and complications of gastro-oesophageal reflux disease
(2002-05-10)
Objective: To clarify the relationship between duodenogastro- oesophageal reflux (DGOR) and gastro- oesophageal reflux disease (GORD) and its complications.
Methods: As persons who have had their gallbladders removed ...
Tissue destruction in arthritis : experimental studies
(2003-11-14)
Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. The sensitivity of radiographic ...
Cholangiocarcinoma in primary sclerosing cholangitis
(2001-10-05)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. ...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
Subcellular localization and signalling of Brutons tyrosine kinase (Btk)
(2002-11-28)
Brutons tyrosine kinase (Btk) is a non-receptor tyrosine kinase related
to the Src family of kinases. Mutations in various parts of the gene have
been shown to cause X-linked agammaglobulinemia (XLA), a primary
immunodeficiency ...