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The normal and ACL deficient knee : an in vivo three dimensional kinematic and electromyographic analysis
(2002-12-27)
(range 2.2 to 8.8 mm) and 3.6 mm (range 2.4 to 5.7 mm) with the knee braced. Neuromuscular changes were observed as a function of bracing. Semitendinosus activity significantly decreased 17% prior to footstrike (P<0.05). Bicep femoris significantly...
Localization and characterization of genes involved in parathyroid tumor development
(2003-03-21)
The overall goal of this thesis has been to identify new genes and characterize them regarding the involvement in parathyroid tumor development. The parathyroid glands are responsible for the control of calcium homeostasis. ...
Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY
(2002-10-04)
Experiences of early adverse life events are more frequent among adult depressed patients than healthy subjects. Studies with non-human primates and rats show that maternal deprivation leads to changes in hypothalamic-pituitary ...
Studies of genetic and environmental influences on Parkinson’s disease
(2004-01-30)
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. Little is known about the etiology of PD. Although several PD genes are known, these are thought to be involved in ...
The importance of Escherichia coli fimbriae in urinary tract infection
(2001-11-16)
Urinary tract infection (UTI) is a major bacterial infectious disease among women. Uropathogenic Escherichia coli is the most dominant causative agent. Clinical observations indicate that repeated cystitis induces a ...
Cholangiocarcinoma in primary sclerosing cholangitis
(2001-10-05)
/10) than CCs from patients without PSC (7/18) (p<0.05). 12% (2/17) of large bile ducts from PSC patients without CC displayed aneuploidy of DNA. In a large cohort of Swedish PSC patients (n=604), we assessed the risk of malignancies in PSC compared...
Adaptation to ischemia with special emphasis on nitric oxide
(2001-08-31)
Nitric oxide (NO) may play an essential role for maintenance of cardiac function and perfusion. Endothelial dysfunction of atherosclerotic vessels may aggravate cardiac ischemia/reperfusion injury. Adaptation to ischemia ...
Appetitive and consummatory ingestive behavior : role of taste, dopamine and NPY
(2001-11-23)
The present thesis has examined the role of taste, dopamine and
neuropeptide Y (NPY) in the regulation of the two phases of ingestive
behavior: appetitive (approaching and handling of food) and consummatory
ingestive ...
Studies on autoimmune diabetes in Latvians and other populations
(2001-10-09)
IDDM is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting B- cells. GAD65 and IA-2 are major B-cell specific autoantibodies and are not found in healthy population. IDDM is associated ...
Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries
(2002-02-25)
General aim: The general objective of this thesis was to evaluate the clinical performance of two new methods for quantification of dental caries - the Quantitative Light-induced Fluorescence method (QLF) and KaVo ...