Search
Now showing items 1-10 of 108
Early detection of colorectal cancer
(2004-03-05)
is highly affected by genetic susceptibility. A family history was obtained from 400/411 (97%) eligible colorectal cancer patients in the County of Västmanland in 1998-2001. Five (1.2%) cases of HNPCC were identified. At least one first-degree relative...
Models for infections in immunodeficiency
(2002-10-25)
Increased susceptibility to infections in immunodeficient patients is a well-known phenomenon. The spectrum of infections reflects the underlying defect. Experimental infections in mouse strains with different types of ...
Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene
(2003-05-23)
kinase inhibitors, genistein, tyrphostin AG17 and tyrphostin AG879, selectively blocked OME- but not TCDD-mediated AhR activation in H411E or HepG2 cells. These data strongly support the action of a tyrosine kinase dependent pathway in OME...
Comparison of stereotactic fine needle aspiration biopsy and core needle biopsy in breast lesions
(2004-04-16)
the 1970th core needle biopsy (CNB) was developed and the method has later been refined. When we started our study 1993, CNB was not used in breast lesions in Sweden.
Biopsy technique: Spinal needles with diameter 0.7 and 0.9 mm were used for S...
Functional studies of the ubiquitin-proteasome system using GFP-based reporters
(2002-11-21)
Ubiquitin-dependent proteasomal degradation is of paramount importance for cellular processes such as cell cycle progression, transcriptional regulation, apoptosis and disposal of misfolded and aberrant proteins. Moreover ...
Surgical treatment of atrial fibrillation : clinical, hormonal and electrophysiological aspects of the maze operation
(2003-01-17)
Background: Atrial fibrillation (AF) is the most common arrhythmia, associated with significant mortality and morbidity, due to hemodynamic impairment and the increased risk of stroke. Traditional pharmacological treatment ...
Aspects of hand function in children with unilateral impairments : caused by obstetric brachial plexus or hemiplegic cerebral palsy
(2002-05-03)
Unilateral arm/hand dysfunction caused by obstetric brachial plexus palsy (OBPP) or hemiplegic cerebral palsy (CP) is most often afflicted on a child in the pre- or perinatal period of life. Despite different origin of the ...
Atopic dermatitis : clinical and epidemiological aspects in children up to four years
(2002-05-22)
with onset of AD during the first year of life than during the second.
Cumulatively up to 4 years of age, 33% reportedly had AD: 27. 1 % of the children without parental atopic history, 37.9% of those with single parental atopic history and 50...
Targets for immune mediated killing of tumor cells and T cell functions in B-CLL
(2003-08-22)
There is a great need for developing and improving treatment alternatives in B-cell chronic lymphocytic leukemia (B-CLL). New therapeutical approaches based on the manipulation of the immune system enable establishment of ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...