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Undergoing stem-cell transplantation : patients perceptions of symptoms, functional status and health-related quality of life
(2002-05-24)
was suffering from. From the day of the stem-cell infusion (T2) and up to approximately 10 days after the transplantation (T5), between 33 % and 54% of the patients reported > 10 simultaneous symptoms. Tiredness (81-91%), loss of appetite (88-93%) and mouth...
Biophysical aspects of contact dermatitis and its prevention
(2004-03-05)
The skin, one of the largest organs of the body, is composed of three layers: the epidermis, dermis and subcutis. The outer most part of the epidermis i.e., the stratum corneum - serves as a protective barrier between the ...
The elite cross-country skier : clinical and sports related functional tests, dance training, injuries and self-related health
(2003-03-14)
The general aim of this thesis was to study cross-country skiers regarding the effect of dance training on joint mobility and muscle flexibility of the spine, hip and ankle and on speed and agility. Another aim was to ...
Cholesterol turnover in acute myelogenous leukemia with special emphasis on regulation of low density lipoprotein receptor expression in leukemic cells
(2001-10-26)
times higher for AML cells than for normal cells and IC50 values correlated with the LDL receptor activity in freshly isolated AM cells (r = 0.53, P = 0.007) indicating that the elevated receptor activity may be a result of decreased sterol sensitivity...
Clinical pharmacokinetics of intravenous ethanol : relationship between the ethanol space and total body water
(2001-10-26)
Introduction: Total body water (TBW) is an important parameter in
pathological states where the normal regulation of fluid balance is
impaired (e.g., during critical illness, congestive heart failure, bum
injury and ...
Health economic assessment of medical technology in chronic progressive diseases : multiple sclerosis and rheumatoid arthritis
(2003-09-26)
This thesis developed a method for economic evaluation in non-fatal chronic progressive diseases, applied to multiple sclerosis (MS) and rheumatoid arthritis (RA). In economic evaluation different treatment strategies are ...
Structure and biological properties of scavenger receptor MARCO
(2002-09-06)
Macrophages are monocyte-derived cells that play an important role in the
innate immune response against invading pathogens. These cells express
several host defense receptors that can be divided into two classes;
those ...
Pulmonary tuberculosis and HIV interaction in a setting with a high prevalence of HIV : clinical, diagnostic and epidemiological aspects
(2002-05-17)
with TB is warranted to reduce transmission.
The highest prevalence of Pneumocystis carinii (P carinii) in expectorated sputum. samples was 10.9% by immunofluorescence assay (IF) and 30.3% by nested polymerase chain reaction (nPCR) among HIV...
In vitro studies of retinoids and arsenic in non-M3 acute myeloid leukemia
(2002-11-08)
, we have investigated what mechanisms that could be of importance for the sensitivity to these drugs. The results showed that there is a pronounced heterogeneity in the sensitivity to the retinoids all-trans-retinoic acid (ATRA) and 9-cis-RA but cells...
Cytomegalovirus after allogeneic haematopoietic stem cell transplantation : complications in the era of CMV-specific antiviral treatment
(2003-12-26)
of CMV-related complications after SCT.
In a study of 584 consecutive allogeneic SCT patients, the overall
probability for CMVdisease was 8.9%, and the risk for death in
CMV-disease 5.7%. The risk varied depending on CMV-serologies in donors...