Search
Now showing items 1-10 of 37
Drug metabolic capacity in Koreans : CYP2D6 & CYP2C19 pheno- and genotype relationships in healthy volunteers and in patients
(2002-05-24)
. The allele frequency of CYP2D6*10 was 0.51 in this Korean population. The MRs of the CYP2D6*1/*1, *1/*10 and *10/*10 genotype groups were significantly different (p<0.0001; Kruskal-Wallis test). It was confirmed that the CYP2D6*10 allele is the major cause...
Skin cancer prevention : readiness to change sun-related behaviours
(2004-04-02)
The general aim of this thesis was to collect data relevant for skin
cancer prevention and to investigate the applicability of the
Transtheoretical Model for sun-related behaviour. Also, to assess the
readiness to change ...
New evidence on germ-cell testicular cancer aetiology
(2004-01-09)
evaluated recent trends in testicular cancer incidence in Northern European countries.
Using data from birth records and from the Swedish Cancer Register, we carried out a casecontrol study of 628 cases and 2,309 controls. We aimed at investigating...
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 and 20 months, and 36 age...
Tissue destruction in arthritis : experimental studies
(2003-11-14)
Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. The sensitivity of radiographic ...
Appetitive and consummatory ingestive behavior : role of taste, dopamine and NPY
(2001-11-23)
The present thesis has examined the role of taste, dopamine and
neuropeptide Y (NPY) in the regulation of the two phases of ingestive
behavior: appetitive (approaching and handling of food) and consummatory
ingestive ...
Minimally invasive hernia surgery
(2003-04-25)
/inflammations, including intestinal obstruction, 58.99. The RR was 2.79 with TAPP and 0.57 with TEP compared to Lichtenstein operated patients....
11beta-Hydroxysteroid dehydrogenase type 1 as a pharmacological target in metabolic disease
(2004-04-08)
and atherosclerotic risk factors including insulin resistance, obesity, dyslipidemia and arterial hypertension. The connection between insulin resistance and diabetes mellitus type 2 has been well established, and the major abnormalities are peripheral insulin...
Nano-electrospray mass spectrometry for the analysis of neurosteroids and related molecules
(2003-03-10)
converted into their oximes which were detected as protonated molecules with 20 times higher sensitivity than the underivatised steroids. The detection limits for the oximes of 3-oxo-delta4, 20-oxo and 17-oxo steroids were 2.5, 5, and 25 pg/µL, respectively...