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Molecular mechanisms of gene activation by nuclear receptors and their associated coregulators
(2001-10-26)
Nuclear receptors (NRs) are ligand-dependent transcription factors. The DNA-bound receptors either positively or negatively regulate transcription of target genes. The receptors regulate transcription through interaction ...
Nephrin cellular trafficking and intracellular interactions
(2004-04-23)
Nephrin is a 180-kDa transmembrane glycoprotein belonging to the immunoglobulin family of cell adhesion molecules. Nephrin has an extracellular part with eight Ig-like motifs, one fibronectin-like domain, a transmembrane ...
Intrathecal adenosine for treatment of acute pain : safety assessments and evaluation in experimental, surgical and labour pain
(2003-11-21)
Adenosine is an endogenous compound present in all cells in the body with a wide range of physiological effects. Exogenous administration of adenosine is used clinically as an antiarrytmic agent and as a vasodilator. In ...
Monitoring pregnancy for improved perinatal outcome in Mozambique
(2002-11-27)
/semirural antenatal clinics in Maputo. Nine percent were lost to follow-up. This cohort was used for anthropometric monitoring of fetal growth to enable the drawing of an SFD growth chart. When selecting sub-populations, nulliparous women were found to lie 0.6 cm...
Observations on essential biochemical data profile in connection with restorative proctocolectomy in humans : vitamin B12 and fat absorption cited
(2001-10-18)
PATIENTS: The material includes 99 patients who consecutively received
handsawn pouch and ileoanal anastomosis, after mucosectomy. Sixty-five
patients were men and forty-four were women. The mean-age was 31.4 (range
17-59) ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which is characterized by relapsing or progressive demyelinating plaques in the brain and spinal cord. It is well established that ...
Hepatitis C virus kinetics during antiviral treatment
(2004-03-05)
It is estimated that 170 million individuals have chronic hepatitis C virus (HCV) infection, whereof 20-30% will develop end stage liver disease within 20-30 years. Antiviral therapy can stop this deterioration and clear ...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...
Lumbar muscle fatigue and recovery : evaluation of electromyography in patients with long-term low-back pain and in healthy subjects
(2002-11-22)
was somewhat higher for patients (ICC>0.6) than for healthy subjects. The initial median frequency and, to a greater extent, the slope were sensitive to the exerted torque. The patients differed from the healthy subjects by lower MVC torque, higher initial...
Clinical application of QLF and DIAGNOdent : two new methods for quantification of dental caries
(2002-02-25)
lesions over a period of 6 months in a randomised, controlled study. In Paper IV, the QLF method was tested for intra- and inter-operator reliability in vivo for the capturing part as well as the image analysis part of the method. In Paper III, Ka...