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Intrathecal adenosine for treatment of acute pain : safety assessments and evaluation in experimental, surgical and labour pain
(2003-11-21)
Adenosine is an endogenous compound present in all cells in the body with a wide range of physiological effects. Exogenous administration of adenosine is used clinically as an antiarrytmic agent and as a vasodilator. In ...
Elucidating the principles of gene regulation in the human genome
(2022-07-28)
Gene regulation is largely controlled by two groups of cis-regulatory elements: (i) promoters that initiate stable mRNAs and (ii) enhancers that generate bidirectionally transcribed unstable enhancer RNAs (eRNAs). While ...
Acute pesticide poisonings in Nicaragua : underreporting, incidence and determinants
(2009-11-24)
Background: Acute pesticide poisonings (APP) are a public health problem in Nicaragua. The quality and coverage of APP´s register, the real incidence of APP, the main determinants, the economic cost of treating cases and ...
Deliberate self-harm : characteristics, clinical correlates and interventions
(2018-03-20)
Background: Deliberate self-harm (DSH) and nonsuicidal self-injury (NSSI) are serious global health problems prevalent among both community and clinical samples. Several studies have suggested that aggression towards others ...
Viral respiratory tract infections in children
(2021-10-28)
The most common infection in humans is viral respiratory tract infections which predominantly present as the ‘common cold’. In some circumstances however, respiratory viruses cause acute lower respiratory tract infections ...