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Human truncated thioredoxin (Trx80) as a novel mitogenic cytokine for white blood cells
(2001-11-27)
Thioredoxin (Trx) is a 12 kDa protein present in all species with a well-conserved active site sequence comprising -Cys-Gly-Pro-Cys-, which catalyzes oxido-reductase reactions. Trx regulates the activity of transcription ...
Metabolism of melatonin : with focus on the influence of cytochrome P4501A2
(2004-01-09)
Melatonin (MT) regulates circadian rhythms. It is produced by
pinealocytes. Their function is regulated by light. MT enters the blood
stream by passive diffusion. It is primarily metabolized in the liver by
6hydroxylation ...
Endothelial function and dysfunction in coronary artery bypass grafting
(2002-01-11)
The integrity of the endothelium is of importance for short- and long-term results following coronary artery bypass grafting (CABG). In this thesis different factors of the endothelial role in the regulation of vascular ...
Studies of genetic and environmental influences on Parkinson’s disease
(2004-01-30)
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. Little is known about the etiology of PD. Although several PD genes are known, these are thought to be involved in ...
Minimally invasive hernia surgery
(2003-04-25)
Lichtenstein (5 vs. 7 days). The time of rehabilitation was shorter after TEP than mesh-plug or Lichtenstein (14 vs. 24.5 vs. 28.5 days). There was a tendency of more pain after Lichtenstein than after TEP or mesh-plug at follow-up. Laparoscopic hernioplasty...
Adaptation to ischemia with special emphasis on nitric oxide
(2001-08-31)
Nitric oxide (NO) may play an essential role for maintenance of cardiac function and perfusion. Endothelial dysfunction of atherosclerotic vessels may aggravate cardiac ischemia/reperfusion injury. Adaptation to ischemia ...
Linkage and association analysis in multiple sclerosis
(2001-09-03)
the possibility of locating susceptibility genes in 5p, 12q23 and 7ptr-15 (Paper I). The highest NPL score in Nordic affected sibpair families was found in 3p14-13. This region is not only formerly suggested by British and Canadian screens, but also contains...
Diabetic osteopathy : a study in the rat
(2012-03-09)
The present study on non-obese Goto-Kakizaki (GK) rats with type-2 diabetes and neuropathy was an attempt to describe and define pertinent features of diabetic osteopathy. Altogether, the study included 33 GK rats aged 12 ...
Particles in small airways : mechanisms for deposition and clearance and pharmacokinetic assessments of delivered dose to the lung
(2004-04-16)
BACKGROUND: Knowledge about lung deposition and clearance from airways of inhaled particles/drugs are essential for evaluation of health effects of inhaled
pollutants and to achieve optimal drug dose to the lung. The ...
Lower limb ischemia in women
(2004-02-27)
Arteriosclerosis is a general disease affecting different parts of the arterial system. In coronary heart disease (CHD) women have different risk factors, symptoms, indication for treatment, interpretation of diagnostic ...