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Cassava processing, consumption and dietary cyanide exposure
(2001-08-17)
Cassava is a major component of the diet of more than half a billion people in the tropics. Cassava is an important crop in the farming system in the tropics because it can be intercropped with many other crops, and yields ...
Functional significance of phosphorylation of rat renal Na+, K+-ATPase by PKA and PKC
(1998-04-02)
. The inhibition of NKA activity by PKA in COS cells is not associated with internalization of the enzyme from the cell surface. Phosphorylation of NKA is implicated in regulation of enzyme activity by 1st messenger. The ß-adrenergic agonist isoproterenol induces...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
and contributes to vascular complications in T2D. Endothelin-1 (ET-1) and arginase are two potent inhibitors of endothelium-derived nitric oxide (NO) and are known to cause ED. Short term studies have shown that blocking ET-1 can improve ED in T2D but no longer...
Subjective well-being in an adult Swedish population : findings from a population-based study
(2009-01-09)
This doctoral thesis examines various factors associated with subjective
well-being (SWB) in an adult Swedish population, aged 20-64 years, using
cross-sectional and longitudinal data. The thesis includes four studies
based ...
Intimate partner violence among women of reproductive age in Nigeria : magnitude, nature and consequences for reproductive health
(2011-01-05)
Background: Intimate Partner Violence (IPV) against women is now recognised as a problem of global magnitude, owing to its detrimental consequences on the health, social and economic welfare of women and their children. ...
On the children's global assessment scale (CGAS)
(2012-02-29)
Rating scales and diagnostic instruments have become increasingly important tools in psychiatric care over the past several decades. Using these standardized tools to collect information and evaluate patients enables ...
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
(Nature Publishing group, 2022-08-18)
Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements. Aberrant Ca2+ handling is a key feature of HF pathophysiology. ...
B cell transcriptomics and immunoglobulin genetics in rheumatoid arthritis
(2022-11-02)
Rheumatoid Arthritis (RA) is a complex autoimmune disease characterized by inflammation of the peripheral joints. The exact disease pathology remains to be elucidated, but it has been hypothesized that autoreactive B cells ...