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Optimization of compliance in epidemiologic research and disease prevention : with special emphasis on PAP-smear screening
(2003-03-14)
The aim of this thesis was to investigate factors affecting attendance in screening for cervical cancer, and to evaluate various measures aimed at increasing compliance to self-administered postal questionnaires and screening ...
B cell transcriptomics and immunoglobulin genetics in rheumatoid arthritis
(2022-11-02)
Rheumatoid Arthritis (RA) is a complex autoimmune disease characterized by inflammation of the peripheral joints. The exact disease pathology remains to be elucidated, but it has been hypothesized that autoreactive B cells ...
Short and long term effects of caesarean section and vaginal delivery
(2010-11-29)
The aim of this thesis was to study short and long term effects after caesarean section (CS) and vaginal delivery. We also studied the difficulty in estimating blood loss at delivery and birth experience estimated nine ...
LXR regulation of hepatic gene expression and pituitary dependent hormones
(2009-03-06)
The liver X receptors (LXRs) are ligand activated transcription factors
involved in the regulation of metabolic genes. LXRs are considered
potential drug targets to treat metabolic disorders, however, unwanted
side ...
Estrogen and liver X receptors in human disease
(2006-11-10)
The nuclear hormone receptors (NRs) are a class of transcription factors that has attracted great interest due to their important roles in animal physiology and metabolism. Studies of knockout (KO) mouse models have indicated ...
Nuclear receptor and Wnt function in developing dopaminergic neurons
(2007-01-26)
The progressive degeneration of dopaminergic neurons in the substantia
nigra is one of the major pathological events associated with Parkinson’s
Disease. Dopaminergic (DA) cell replacement therapy has emerged in recent
years ...
Physical exercise as a targeted therapy in idiopathic inflammatory myopathies
(2013-10-25)
Idiopathic inflammatory myopathies are comprised of polymyositis (PM) and dermatomyositis (DM) with muscle impairment being the primary clinical feature. With the currently recommended treatment regimen, a majority of ...
Dietary effects on gene regulation and function in human adipose tissue in obesity
(2007-05-04)
Obesity is an excess of body fat that develops from both genetic and environmental factors, leading to a disturbed balance between energy intake and energy expenditure. It is closely associated with insulin resistance, ...
Aspects of participation in sigmoidoscopy screening for colorectal cancer
(2007-05-25)
Colorectal cancer is an important health problem due to a high morbidity and mortality but it is curable at an early stage and is therefore ideal for screening. Population-based screening of the average risk population ...
Factors affecting attendance at population-based mammography screening
(2002-01-11)
The aim of the studies described in this thesis was to explore factors affecting attendance at outreach mammography screening, and to assess possible associations between socioeconomic factors and breast cancer ...