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Residential radon exposure and lung cancer : risk assessment based on epidemiologic data
(2001-05-16)
Inhalation of decay-products from radon in dwellings is the main source
of exposure to ionising radiation for the population of many countries.
With an average concentration in dwellings of about 100 Bqm-3 indoor
radon ...
Structural studies of lipopolysaccharides expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains
(2012-08-31)
The present thesis describes lipopolysaccharide (LPS) structures expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains. LPS is a major surface component of Gram-negative bacteria. Structural ...
Leukotriene A4 hydrolase : identification of amino acid residues involved in catalyses and substrate-mediated inactivation
(2001-09-14)
Leukotriene (LT) A4 hydrolase catalyzes the committed step in the
biosynthesis of LTB4, a classical chemoattractant and immuine-modulating
lipid mediator involved in inflammation, host-defense against infections,
and ...
A multi-omics approach to uncover estrogen receptor (ER) and activator protein 1 (AP-1) signaling networks in breast cancer
(2019-09-27)
Estrogen receptor (ER) binds to DNA indirectly through other transcription factors (e.g. AP-1) to modulate gene expression, which is a tethering mechanism. The ER/AP-1 crosstalk plays an important role in tamoxifen therapy ...
Mobile teleconsultations in acute burn care : acceptance and user-experience among emergency care providers in resource-poor settings
(2019-10-08)
Background: Burn injuries are a global health problem with severe consequences for those affected and nearly 95% of all burns occur in low- and middle-income countries (LMICs). While minor burns can be treated locally such ...
Vaccination against Her2/neu : expressing cancer using chimeric virus-like particles
(2009-04-24)
Thanks to the development of vaccines, children are these days protected
against infectious diseases like polio, diphtheria and tetanus simply by
receiving a few injections. Imagine a scenario where these injections
would ...