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Structural studies of lipopolysaccharides expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains
(2012-08-31)
The present thesis describes lipopolysaccharide (LPS) structures expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains. LPS is a major surface component of Gram-negative bacteria. Structural ...
Calcium signaling and network activity : mathematical modeling and molecular mechanisms
(2017-05-17)
The calcium (Ca2+) ion is a versatile second messenger present in all cells. It is involved in such diverse processes as cell division, differentiation, vesicle transport and muscle contraction. Its widespread applicability ...
The importance of fat and alcohol for progression and prognosis in chronic liver disease
(2016-04-06)
Chronic liver disease is an increasing cause of global morbidity and mortality. The popular
belief is that liver disease is caused mainly by alcoholic liver disease or viral hepatitis.
However, the most common cause of ...
Rheumatoid arthritis as a modifier of periodontitis
(2007-01-19)
Periodontitis is a chronic tissue-destructive condition in which the
tooth-supporting collagen fibers of ligament and bone are broken down
mainly by the host s overreactive immune inflammatory response. The
relation between ...
Studies of molecular mechanisms of action of TNF antagonists in rheumatoid arthritis
(2004-11-26)
Rheumatoid arthritis (RA) is a common chronic inflammatory disease
characterized by progressive bone destruction that leads to joint
deformity and physical disability. Even though several therapeutic drugs
are available, ...
Aprotinin for reduction of bleeding and transfusions in patients on clopidogrel undergoing urgent coronary surgery
(2009-05-08)
Background: An increased proportion of patients with acute coronary syndrome undergo coronary surgery while treated with clopidogrel, an irreversible platelet ADP-receptor inhibitor. Clopidogrel in combination with aspirin ...
The small bowel and functional dyspepsia : peptide hormones and neurotransmitters
(2013-11-15)
Functional dyspepsia (FD) is believed to be caused by pathophysiological changes in the upper gut. Gastro-intestinal motility, epithelial transport and signalling is associated with the metabolism of nutrients and the ...
Markers of inflammation and cardiovascular disease in dialysis patients : variability and prognostic value
(2016-04-15)
Patients with end-stage renal disease are burdened with a high cardiovascular morbidity and mortality. Inflammation is a common feature in these patients and strongly associates with cardiovascular complications and outcome. ...
Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications
(2015-10-23)
Class I viral fusion glycoproteins facilitate fusion of the viral envelope with cell membranes and entry of the virus into the cell, through extensive short sequence-specific interactions. Regions mediating these interactions ...
Mild traumatic brain injury : clinical course and prognostic factors for postconcussional disorder
(2006-12-29)
Background: Mild traumatic brain injury (MTBI) is frequent and sometimes leads to
persistent disability. It remains a matter of controversy as to what
impact the different main determinants - brain injury factors ...