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Salivary function after pediatric bone marrow transplantation
(2000-05-05)
BMT, at 3, 6, and 12 months after treatment, and then at yearly controls. The results were compared with those of a reference group of children stratified for age and sex. A multivariate logistic regression analysis of 40 possible risk factors...
Impact of infertility and assisted reproductive technology on cancer risk
(2018-05-07)
Ovarian stimulation drugs, in particular those used in assisted reproductive technology (ART)
treatments for infertility, have been suspected to influence cancer risk. In addition, infertility
per se may be a risk factor ...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Time resolved functional brain networks : a novel method and developmental perspective
(2022-01-28)
Functional neuroimaging has helped elucidating the complexity of brain function in ever more detail during the last 30 years. In this time the concepts used to understand how the brain works has also developed from a focus ...
Human parvovirus B19 : studies on the pathogenesis of infection
(2001-05-11)
Human parvovirus B19 (B19) causes the common childhood disease erythema infectiosum. The virus is transmitted by the respiratory route, infects erythroid progenitor cells, and thereby inhibits erythropoiesis. The seroprevalence ...
TRIM21/ Ro52 in B cell pathology
(2013-01-25)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease affecting 0.2% of the population. Several B cell aberrances have been linked to pSS, such as autoantibody production, hypergammaglobulinemia and B cell ...
Integrative omics data analysis to discover novel signatures in complex diseases
(2023-03-09)
Apart from diseases caused by the defect of a single gene, most diseases are highly complex and are usually caused by a combination of biological and environmental factors. In the biological context, cellular processes are ...
Stress, depression, and other psychiatric disorders : an epidemiological approach to studying the causes and consequences for in vitro fertilization outcome and polycystic ovary syndrome
(2017-04-20)
Reproductive epidemiology, psychiatric epidemiology, and pharmacoepidemiology come together in this thesis which is comprised of four studies and divided into two parts.
Part 1 examines the impact of stress and ...
Multiple sclerosis : from genetic variants to biomarkers
(2019-09-06)
Multiple sclerosis (MS) is a common chronic autoimmune and neurodegenerative disease of the central nervous system (CNS). MS is a debilitating disease that affects young adults, especially females. Why we develop MS? Is ...
Behavior change intervention and fear of hypoglycemia in type 1 diabetes
(2012-11-07)
Introduction: Individuals with type 1 diabetes require lifelong insulin supply as well as behavioral adjustments for good treatment result. Only a minority reach the goal for glycemic control set in order to reduce the ...