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Anticipating, experiencing and valuing the transition from worker to retiree : a longitudinal study of retirement as an occupational transition
(2000-04-14)
The general aim of this thesis was to explore and understand the retirement process from an occupational perspective. Exploration of the retirement process included attitudes, preparations and expectations before retirement, ...
Pulmonary surfactant proteins B and C : molecular organisation and involvement in respiratory disease
(2000-11-23)
bubble surfactometry, mass spectrometry and reversed-phase HPLC. (Cys48Ser)SP- B, both in a phospholipid environment and in organic solvents, is largely monomeric and exhibits low activity at concentrations < ~ 2 mM, while at higher concentrations...
Pelvic pouch in ulcerative colitis : surgical refinement and long-term mucosal outcome
(1999-11-05)
defunctioning loop ileostomy, 2. to elucidate the incidence of pouchitis and evaluate possible predictive factors, 3. to investigate the occurrence of, and possible risk factors associated with neoplastic transformation of the pelvic pouch mucosa, and 4...
Prospective cohort studies of disability pension and mortality in a Swedish county
(2007-09-04)
The overall aim of this thesis was to study risk factors for disability
pension, focusing on sociodemographic risk factors and sick-leave
diagnoses, and also to investigate the risk of mortality among disability
pension ...
Breast cancer natural history models and risk prediction in mammography screening cohorts
(2022-03-31)
In this thesis, the foundations are laid for a new natural history model for breast cancer—specifically designed to take advantage of detailed screening cohorts. Three diverse applications of this model are then presented. ...
Lymphangiogenesis and lymphatic metastasis
(2005-11-18)
the accumulation of peritumoral lymphatic vessels and promoted metastasis to the regional lymph nodes. The mechanism by which VEGF-A induces lymphangiogenesis might involve both direct effects, through activation of VEG17R-2 expressed on lymphatic endothelium...
T cells in solid tumors : investigating the immunomodulation in the tumor microenvironment
(2018-09-03)
contradictory finding that a high FOXP3+ tumor infiltrating lymphocyte (TIL) number correlates positively to survival. In here, we answered that FOXP3+ CD4+ T cells in the tumor were real Tregs which protectively regulated tumor invasiveness by suppressing MMP2...
Healthcare financing challenges and opportunities to achieving universal health coverage in the low- and middle-income country context
(2020-02-05)
% confidence interval (CI): 20.9–24.8] or 0.32 USD. Monthly income, occupation, geographic location and educational level were the main determinants of WTP. Study III suggested that the insured of CBHI were 2.111 (95% CI: 1.458- 3.079) times more likely than...
Diet and gastrointestinal cancer : one-carbon metabolism and other aspects
(2006-11-23)
.58) for esophageal cancer, 1.90 (1.38-2.60) for gastric cardia cancer, 1.68 (1.29-2.19) for gastric cancer, 2.28 (0.91-5.71) for pancreatic cancer, and 0.84 (0.75-0.95) for colorectal cancer. For colorectal cancer, the summary odds ratio for the MTHFR 1298CC versus...
Genetic determinants of breast cancer risk
(2011-01-19)
The main purpose of this thesis was to identify genetic risk factors using both hypothesis-based and hypothesis-free approaches.
In an attempt to identify common disease susceptibility alleles for breast cancer, we ...