Search
Now showing items 1-10 of 10
The role of neuropeptides in spinal nociceptive mechanisms with special emphasis on galanin, neuropeptide Y and orphanin FQ/nociceptin
(2000-01-21)
Several peptides present in sensory neurons and in the spinal cord have been recognized to have inhibitory action in nociception. In this thesis, we have used the flexor reflex preparation in rats to study the role of ...
Associations of breast cancer risk prediction tools with tumor characteristics and metastasis
(2020-04-23)
Purpose: The association between established risk factors for breast cancer and subtypes or prognosis of the disease is not well known. We analyzed whether the Tyrer-Cuzick–predicted 10-year breast cancer risk score (TCRS), ...
RNA systems for NMR studies in vitro and in vivo
(2022-04-05)
NMR spectroscopy is an excellent tool to study the structure-function relationship of RNA. Such measurements are usually performed in vitro, which requires large amounts of isotope- labeled sample in high purity and can ...
Genetic determinants for susceptibility, progression and prognosis of prostate cancer
(2015-10-23)
Prostate cancer is the most commonly diagnosed form of non-skin cancer among men in developed countries. Although a large proportion of patients eventually die from the disease, many indolent tumors are found via prostate ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Redesigning an emergency department for interprofessional teamwork : a longitudinal evaluation of the impact on patient flow and team behaviour
(2020-05-19)
Objective: Crowding in emergency departments (EDs) has negative effects on patients and staff, whereas effective teamwork in healthcare has positive effects. Triage interventions and streaming of specific patient categories ...
Mechanisms of women's own-gender bias and sex differences in memory for faces
(2012-09-06)
There are sex differences in some cognitive functions. For example, earlier studies have shown that women outperform men on face recognition tasks, and women, in contrast to men, show an own-gender bias (i.e., women typically ...
Pharmacological and analytical studies of the cyclin dependent kinase inhibitors
(2009-10-30)
Cyclin-dependent kinases (Cdks) play a key role in the regulation of cell cycle progression and RNA transcription. Deregulation of Cdks has been associated with several malignancies, neurodegenerative disorders, viral and ...
Becoming a mother at an advanced age : pregnancy, outcomes, psychological distress, experience of childbirth and satisfaction with life
(2013-11-15)
The objectives of this thesis were to investigate adverse pregnancy outcomes, and pregnancy and psychological experiences in women who become mothers in the later phase of the reproductive period. The age of first-time ...
Molecular characterization of phenothiazines in experimental cancer therapy : new tricks of an old drug revealed
(2012-04-04)
Cancer is characterized by uncontrolled malignant proliferation of cells that eventually interfere with tissue/organ functions. Traditionally, cancer is treated with chemo- and/or radiotherapy when surgery is not an option. ...