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Triglyceride-rich lipoproteins : postprandial metabolism and composition in relation to atherosclerosis
(1998-04-24)
A relationship between postprandial lipaemia and coronary heart disease (CHD) was established as early as the 1950s. Since then, most attention has been paid to postprandial triglyceride-rich lipoproteins (TRLs) of intestinal ...
Suicide attempt and genes : psychiatric and genetic characteristics of suicide attempters
(1999-11-12)
hydroxylase (TPH), serotonin transporter (SERT) and serotonin receptor 2A (5-HT2A). In the association study investigating the TH polymorphism, a significant difference in the TH allelic distribution was observed among the suicide attempters with a diagnosis...
Endometriosis and ovarian reserve : inflammation and prognostic markers
(2008-04-18)
Introduction: Endometriosis is a common, benign gynecological disease,
associated with pelvic pain and infertility. It is generally thought to
be caused by retrograde shedding of menstrual tissue with subsequent
attachment ...
Pathophysiological factors and genetic association in endometriosis
(2011-01-27)
Introduction: Endometriosis is a common benign gynecological disease where endometrial tissue forms lesions outside the uterine cavity. Endometriosis is estimated to affect about 10% of women of reproductive age, rising ...
Interactions between innate immune effectors and multidrug resistant bacteria
(2020-10-14)
Antibiotic resistance is an increasingly difficult problem in the clinic, where conventional antibiotics are failing, and new alternative solutions are in high demand. Infections caused by Gram-negative bacteria with multi ...
Investigations of Porphyromonas gingivalis as a possible trigger of autoimmunity in the development of rheumatoid arthritis
(2018-03-29)
Rheumatoid Arthritis (RA) is a severe autoimmune disease affecting 0.5-1% worldwide. Patients suffer from pain, disability, chronic joint inflammation, comorbidities and increased mortality. Although, the aetiology of RA is largely unknown, both...
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level
(2013-08-23)
Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines ...
Expression and function of TRP channels in peripheral sensory neurons
(2009-05-19)
in sensory neurons. To elucidate new functional roles, an expression study measuring differential regulation of all TRP channels in rats during development of neuropathic pain was conducted. Downregulation was evident for TRPM6, A1, V1, M8, C3, C4 and C5...
Epidemiological studies of vacuum extraction delivery : incidence, risk factors and subsequent childbearing
(2014-11-10)
The aim of this thesis was to bring focus on factors and outcomes associated with vacuum
extraction delivery (VE). Delivery by VE is associated with both maternal risks (such as
obstetric anal sphincter ruptures, postpartum ...