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Pathophysiological factors and genetic association in endometriosis
(2011-01-27)
Introduction: Endometriosis is a common benign gynecological disease where endometrial tissue forms lesions outside the uterine cavity. Endometriosis is estimated to affect about 10% of women of reproductive age, rising ...
Etiologic, diagnostic and prognostic factors in vulvar cancer
(2011-05-24)
Vulvar Squamous Cell Carcinoma (VSCC) can be divided into two subgroups basaloid and/or warty (HPV-associated) and keratinizing/non-keratinizing carcinomas (not HPV-associated).
The inguinal lymph node status ...
Immunity to malaria: importance of exposure and parasite polymorphism
(2014-04-25)
Malaria continues to carry an intolerable burden of disease and mortality, predominantly on children in Sub-Saharan Africa. An efficacious vaccine would be a powerful tool in the combat against malaria. Further understanding ...
On the clinical assessment of persistent fatigue and pain
(2023-01-04)
Patients with persistent fatigue and pain, most of them women, often struggle with decreased function and related concerns. They commonly receive an inconclusive investigation and a delayed diagnosis. Neuropathic aspects ...
Individually tailored internet-based treatment for depression and comorbid conditions
(2018-12-21)
Background: Depression is a large societal problem. People suffering from depression are heterogeneous and have a high degree of comorbid conditions. Pharmacological treatment is widespread, but not effective for all ...
Identification and evaluation of novel prognostic genetic markers for childhood acute lymphoblastic leukemia
(2017-03-02)
Childhood acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer today. Due to advances in risk stratification and treatment, survival rates have increased drastically the last decades. Currently, ...
Role of c-Myc in the regulation of rDNA transcription by RNA polymerase I
(2010-04-30)
Ribosomal biogenesis and protein translation are finely coordinated with cell proliferation. All three RNA polymerases Pol I, II, and III are utilized for highly efficient and accurate ribosome production. The transcriptional ...
Beyond mammography : an evaluation of complementary modalities in breast imaging
(2023-03-31)
Breast cancer is the main cause of cancer death among women worldwide and the goal of mammography screening is to reduce breast cancer-specific mortality. The reduction of the sensitivity of mammography for detecting cancer ...
Immune and autoimmune responses to HIV-1 in mucosa and other tissues
(1999-10-08)
The aim of these studies was to evaluate routes and devices for administration of HIV-1 DNA vaccines. In particular we were interested in mucosal routes for the induction of immunity at mucosal surfaces.
We studied ...
Fighting cardiometabolic disease : validation of new experimental models and therapeutic targets
(2020-05-14)
The prevalence of cardiometabolic diseases (CMD) such as atherosclerotic cardiovascular diseases, type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), has grown dramatically during the last decades. Hence, ...