Search
Now showing items 1-10 of 31
Early diagnosis of Alzheimer's disease : focus on quantitative EEG in relation to genetic, biochemical and neuroimaging markers
(1999-04-02)
misclassified as AD patients on the basis of these EEG variables might be at risk for developing the disease.
2) The APOE [epsilon]4 allele did not influence disease severity as measured by alpha/theta ratio, an index of EEG slowing, and by the cerebral...
Structural studies of lipopolysaccharides expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains
(2012-08-31)
The present thesis describes lipopolysaccharide (LPS) structures expressed by non-typeable Haemophilus influenzae and Haemophilus parainfluenzae strains. LPS is a major surface component of Gram-negative bacteria. Structural ...
CYP2D6-polymorphism and effect of adjuvant tamoxifen in breast cancer patients
(2023-09-04)
activation of tamoxifen due to polymorphism in the CYP2D6 gene has been suggested to influence the effect of the treatment, but data are inconsistent. Our previous study in a smaller cohort of tamoxifen treated early breast cancer diagnosed 1998...
Epidemiological studies on type 2 diabetes : assessment of diabetes risk factors and study participation
(2012-02-02)
Type 2 diabetes is a disease with increasing prevalence. Better knowledge of risk factors may form the bases for specific interventions and preventive measures. The aim of this thesis was to contribute to the knowledge on type 2 diabetes...
The matter of white and gray matter in cognitive impairment
(2017-08-03)
Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the most ...
Extremely preterm birth : brain imaging and outcome at early school-age
(2018-05-09)
There has been a dramatic increase in the survival of extremely preterm children over the last decades, and the awareness of the consequences of extremely preterm birth on the developing brain is increasing. This thesis ...
Mathematical modelling of insulin signalling : effects on glucose metabolism in skeletal muscle
(2010-04-13)
The use of models to understand complex phenomena is indispensable to the
scientific community. The advantage of a model is that it simplifies the
phenomena under study. However, a model should be only as complex ...
Understanding inflammatory mechanisms in rheumatic diseases
(2014-11-05)
Rheumatoid arthritis (RA), Psoriasis (Ps) and Psoriasis arthritis (PsA) are chronic inflammatory autoimmune disorders, where primary targets are peripheral joints, skin and skin/joints respectively. Both innate and adaptive ...
Understanding inflammation requires neuroscience
(2022-03-01)
Inflammation and its resolution are processes subject to neural regulation (1). The best-characterized immune-regulating reflex is the “inflammatory reflex”, in which the efferent branch of the vagus nerve plays a central ...
Distal radius fractures : epidemiology and aspects of surgical management
(2020-11-06)
Distal radius fractures (DRFs) are the most common fractures treated by physicians. About 20% of all DRFs are treated surgically. The main surgical methods are volar plate fixation, external fixation and percutaneous ...