Search
Now showing items 1-10 of 10
Mass spectrometry in peptide and tumor marker analysis
(1999-03-05)
of peptides containing Cys, this amino acid was converted to 4-tialaminine.
The protein expression patterns of oncogene-transformed cell lines and tumor cells of different malignancies from breast, lung and ovary were analyzed by 2-D gel electrophoresis...
Host responses to human neural cell therapy in spinal cord injury
(2013-09-24)
mononuclear cells (PBMCs) and up-regulated CD4+CD25+forkhead box P3+ T cells, identified as induced regulatory T cells. However, hESC-NPCs but not hfNPCs dose-dependently triggered allogeneic PBMC proliferation, which may be at least partly due to TGF...
Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells
(2008-10-17)
Osteoblasts play a fundamental role in determining bone structure and function. These cells originate from mesenchymal stem cells (MSCs) and through proliferation and differentiation develop into preosteoblasts and then ...
Adaptation of Salmonella enterica to antibiotics and innate immunity effectors
(2021-02-22)
Salmonella enterica is a bacterial pathogen causing major morbidity and mortality in low- and middle-income countries. The bacteria can cause a wide range of disease, ranging from the severe systemic disease typhoid fever ...
Anatomical and functional characterization of serotonergic neurocircuitry
(2016-12-19)
The serotonin system arises from a small collection of brainstem structures called the raphe nuclei and innervates much of the central nervous system. A relatively small number of serotonin neurons modulate a wide variety ...
Investigating the role of p73 proteins in controlling the tumor microenvironment
(2020-10-20)
Cancer is a multifactorial disease governed by oncogenes and tumor suppressors that not only impact on the behavior of the cancer cells but also influence many processes in the surrounding tumor microenvironment. The most ...
Epidemiological aspects of sarcoidosis : risk factors and long-term consequences
(2021-01-27)
predictors in sarcoidosis. We found a 2.4-fold increased relative risk of heart failure associated with sarcoidosis that was higher during the first two years since sarcoidosis diagnosis and in individuals without a history of ischemic heart disease. Diabetes...
Deuterium-L-DOPA : a novel means to improve treatment of Parkinson's disease
(2012-08-31)
L-DOPA, the precursor of dopamine, is administered to restore dopamine deficiency in Parkinson´s disease (PD) patients. L-DOPA initially provides a sustained symptomatic relief with superior efficacy as compared to other ...
Vaccination against Her2/neu : expressing cancer using chimeric virus-like particles
(2009-04-24)
Thanks to the development of vaccines, children are these days protected
against infectious diseases like polio, diphtheria and tetanus simply by
receiving a few injections. Imagine a scenario where these injections
would ...
Pathogenic mechanisms behind dysregulated angiogenesis with focus on HIF and IGF-I signaling
(2013-09-12)
Angiogenesis is a complexly regulated process activated to assure cells with normal supplies of nutrients and oxygen. Playing such an essential role in the homeostasis of tissues, it is critical to understand its physiology ...