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Navigating the oligodendroglial chromatin landscape using high-throughput single-cell epigenomics
(2024-04-19)
The central nervous system (CNS), which includes the brain and spinal cord, is a remarkably complex system composed of billions of cells controlling everything ranging from basic metabolic functions to higher executive ...
Organization of signaling networks during receptor-mediated membrane protein trafficking
(2008-04-04)
The mechanisms by which receptor signals are organized in a synergic/hierarchical manner in time and space during regulation of integral membrane protein traffic remain a present challenge. The aim of this study was to ...
Cellular and synaptic properties in the lamprey striatum
(2012-09-07)
The striatum is the main input structure of the basal ganglia, a group of subcortical nuclei that are central to the control of different patterns of motor behaviours and for the selection of actions, a fundamental problem ...
Prime-boost immunization strategies against HIV-1
(2007-10-12)
Since the start of the global HIV epidemic in 1981, more than twentyfive
million people have succumbed to AIDS-related diseases. The epidemic is
most severe in Sub-Saharan Africa, where twentyfive million people are
currently ...