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MRI quantification of multiple sclerosis pathology
(2021-02-02)
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease and a common cause of neurologic disability. MS pathology is characterized by demyelination, neuroaxonal loss and atrophy. ...
Long-term sickness absence : aspects of society, work, and family
(2010-04-01)
Sickness absence has varied considerably in Sweden over time and
increased substantially between 1997 and 2002, especially among women.
The composition of such absence has also changed in that there have been
increases ...
Socially dependent avoidance learning : mechanisms of adaptive behavior
(2014-08-08)
Many aspects of human social behavior are likely to be shaped by punishment, threats of punishment, and avoidance of punishment. However, surprisingly little is known about the psychological mechanisms underpinning these ...
Structural and functional studies of Malassezia sympodialis-derived allergens
(2008-03-21)
Atopic eczema (AE) is a chronic inflammatory skin disease characterised
by pruritic (itchy) skin lesions. The pathogenic mechanisms underlying AE
are still unclear, although several factors such as genetic
predisposition, ...
Oral mucositis and periodontal disease in patients with primary or acquired immunodeficiencies
(2013-09-11)
The infection and inflammation in the oral cavity are commonly related to the skewed interaction between host immunity and inhabiting microorganisms. Both primary and acquired immunodeficiency conditions are frequently ...
The small bowel and functional dyspepsia : peptide hormones and neurotransmitters
(2013-11-15)
Functional dyspepsia (FD) is believed to be caused by pathophysiological changes in the upper gut. Gastro-intestinal motility, epithelial transport and signalling is associated with the metabolism of nutrients and the ...
Immunoregulatory properties of CD137-CD137 ligand axis in tumours and chronic inflammatory conditions
(2022-03-11)
CD137 (4-1BB/TNFRSF9) is a member of the TNF receptor superfamily. CD137 expression is activation-dependent, and usually reported on T cells and NK cells. Its natural ligand is CD137 ligand (CD137L), mainly found on ...
Fatigue : perceived, described and assessed by persons with systemic lupus erythematosus
(2012-10-04)
Fatigue is an individual and subjective sensation interfering with daily living for patients with several chronic conditions. Systemic lupus erythematosus (SLE) is characterized by inflammation in different organs combined ...
Functional gastrointestinal disorders : co-morbidity and non-somatic aspects
(2008-05-19)
Aims of the thesis: The first aim, (Study I) of this thesis was to
compare co-morbidity of the reported symptoms and its relation to
healthcare seeking behaviour among non-patients who had persistent
functional ...
Living with inflammatory bowel disease : health-related quality of life, worries, and stress
(2012-01-04)
Background: Patients with inflammatory bowel disease have a number of worries and concerns related to the disease, and in comparison with a general population their health-related quality of life is impaired. These patients ...