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Genetic analysis of human astrocytic gliomas : xenografts as a research tool
(1999-11-26)
Cancer is a genetic disorder of somatic cells. An accumulation of genetic changes is believed to result in neoplastic transformation and malignant progression. In humans, astrocytic gliomas are the most common primary ...
Characterizing the effects of weight loss on human adipose tissue gene transcription and cell composition
(2023-05-05)
Obesity is a globally prevalent metabolic disease that affects more than one billion people according to the World Health Organization and the number continues to increase. Obesity has detrimental effects on health and ...
Roles of Myc and Mad in cell cycle and apoptosis
(2006-05-12)
The Myc network proteins are key mediators in regulation of cell growth, differentiation and apoptosis. They are basic region hehx-loop-helix/leucine zipper (bHLH/Zip) transcription factors that require hetero-dimerization ...
Aspects of diverting stoma and ERAS in rectal cancer surgery
(2016-04-25)
Annually, nearly 2000 patients are diagnosed with rectal cancer in Sweden. To date, the only known curative treatment is surgery and low anterior resection (LAR) is the operation of choice for tumours in the middle rectum. ...
Lost in transition? A study of newly graduated teachers' experiences during the initial period of employment
(2011-04-06)
The most crucial factors affecting burnout and work engagement when entering employment were feelings of competence to satisfactorily perform one’s work, the discrepancy between previous expectations and the actual conditions ...