Search
Now showing items 1-3 of 3
Genetic and epigenetic factors shaping the transcriptome in multiple sclerosis and its animal model
(2014-11-21)
Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. Susceptibility to develop MS is determined by both genetic and environmental factors. The epigenome resides in the ...
Insulin-like growth factor 1 receptor, novel functions and future possibilities
(2017-09-01)
Insulin like growth factor-1 receptor (IGF-1R) has been shown to be important for cancer cell growth and survival, and is often overexpressed in malignant and premalignant tissues. Ligand binding to IGF-1R induces ...
Dynamic regulation of aryl hydrocarbon receptor function and activity by different stimuli
(2010-03-26)
Cells have to sense and adapt to changes in their surrounding environment. Most of the cellular responses to environmental and developmental stimuli are mediated by PAS (Per-ARNT-Sim) proteins. A member of this family of ...