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Glomerulopathy in normoalbuminuric adolescents with type 1 diabetes : relations between structure, function, metabolic control and ambulatory blood pressure
(2005-04-29)
An increase in the incidence of type 1 diabetes in childhood has been
reported in several countries, especially among the youngest children.
Although clinically apparent diabetic vascular disease is rare in
children and ...
Exploring novel roles of tumor pericytes
(2015-11-19)
Tumor biology has been extensively studied over the last few decades, with a principal focus
on how neoplastic cells obtain cellular immortality. A number of oncogenes and tumor
suppressor genes have been uncovered that ...
Dynamic protein trafficking of the nuclear membrane and peroxisomes
(2009-01-30)
The cell nucleus is enclosed by the nuclear envelope (NE), a double lipid membrane separating the nucleoplasm from the cytoplasm. Transport of macromolecules between the nucleus and the cytoplasm takes places through nuclear ...
Organic dust-induced signaling in human pulmonary epithelial cells : emphasis on effects of cAMP modulation
(2005-09-09)
To study signaling transductions in innate immunity a model system was applied where A549 alveolar epithelial type II cells were used as target and organic dust collected in swine confinement buildings as stimulus. The ...
Understanding and targeting the architecture in cancer : novel therapies in neuroblastoma and medulloblastoma
(2021-03-31)
Cancer is the second leading cause of death worldwide after cardiovascular diseases. In Sweden, childhood cancer is the most common cause of death in children 1-14 years of age. Owing to advances in treatment and a better ...
Novel therapeutic targets in pediatric neural tumors
(2018-02-16)
The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. The ...