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Cancer proteomics : method development for mass spectrometry based analysis of clinical materials
(2009-11-06)
To improve cancer treatment, biomarkers for diagnostics and therapeutic guidance are desperately needed. Mass spectrometry (MS) based proteomics is one of the most promising methods for biomarker discovery. Clinical materials ...
Development of radiometal-based labelling techniques and tracers for non-invasive molecular imaging
(2022-03-03)
Metallic radionuclides, radiometals, have an important role in nuclear medicine. Their straightforward coordination radiochemistry allows for a large variety of applications. The similarities and differences between the ...
Oxysterol receptors LXRs and coregulators in cholesterol metabolism and inflammatory transrepression pathways
(2011-06-08)
The LXRs are important sensors and regulators of cholesterol homeostasis in several metabolic tissues including liver, intestine and macrophages. They regulate target genes involved in cholesterol-, lipid- and carbohydrat ...
Helicobacter pylori infection among children in Riga, Latvia
(2006-12-29)
Aims: To identify the prevalence of H.pylori among asymptomatic children and their parents in Riga, Latvia. To study the age of acquisition for H.pylori and the risk factors and symptoms associated with H.pylori infection. ...
Systems biology approaches to investigate mechanisms of obstructive lung diseases
(2022-09-23)
Both asthma and chronic obstructive pulmonary disease (COPD) are obstructive lung diseases with a large impact on global health, causing 400 000 and 3 million deaths respectively each year. The numbers may be underestimated, ...