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Assignment and assessment of orthology and gene function
(2004-01-30)
Several genomes from different species have been sequenced over the last years, most notably the human genome. An important task of computational biology is to classify and functionally annotate the large amount of sequence ...
Genetic predisposition and dietary factors in relation to adiponectin and insulin resistance
(2013-08-30)
Diabetes mellitus is a global health problem, owing to the high prevalence and enormous associated economic burden. Insulin resistance is a critical condition to the development of type 2 diabetes (T2D). Adiponectin, a ...
Quantitative MRI biomarkers of neurodegeneration in multiple sclerosis
(2022-02-28)
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of ...
On diagnostic procedures in pulmonary embolism
(2008-10-03)
Pulmonary embolism (PE) and deep venous thrombosis (DVT) are two entities of venous thromboembolism (VTE). PE is a common cause of mortality and morbidity. The symptoms and signs of PE are difficult to interpret, and the ...
Thrombotic and cardiac disease in the antiphospholipid syndrome
(2021-04-16)
The antiphospholipid syndrome (APS) is a highly heterogeneous disease that presents with obstetric complications and/or thromboembolic events that can hit any side of the vascular tree in an unpredictable way. The common ...