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T cells and costimulatory factors in myasthenia gravis
(2005-09-09)
with antibodies targeting CD25. This molecule is expressed on activated cells. The levels of activated T cells, serum levels of IL-10 as well as the soluble costimulatory molecules sCD28, sCD80, sCD86 and sCD152 decreased, suggesting a normalization...
Functional analysis of genetic variants in putative low penetrate breast cancer genes
(2004-09-03)
difference in allelic frequency was found between the breast cancer patients and controls for either polymorphism. A novel promoter polymorphism was identified at position -152 with a similar frequency of the rare C allele in both breast cancer patients...
Exposure and acceptance in patients with chronic debilitating pain : a behavior therapy model to improve functioning and quality of life
(2009-01-16)
A large number of patients suffer from reduced functioning and quality of
life due to longstanding pain. The importance of psychological factors is
undisputable and there is today substantial empirical support for
treatments ...
On gallstone disease : complications and surgical treatment
(2005-11-18)
episode predicted difficulty in the overall operation. Predicting difficulties in dissection of Calot's triangle was most difficult and not dependent upon CRP value. Among 152 776 cholecystectomies registered in the Swedish Inpatient Registry, 613 (0...
Glutaredoxin 3 from Escherichia coli : NMR structure analysis and structural aspects of the enzymatic mechanism
(1998-10-30)
to Va152 of Grx3. The structure also suggests the presence of a second glutathione binding site which could explain the observed specificity for reduction of glutaredoxin-glutathione mixed disulfides by glutathione.
Except for the active site, the NMR...
Protein and lipid interactions of mammalian antibacterial peptides
(2001-03-09)
activity against B. megateriumin Bm11 Among these, two Cterminal histone H1A fragments were characterised, corresponding to Lys152-Lys222 and Lys167-Lys222, and both were modified by conjugation of the C-terminal carboxyl group of the tripeptide Arg...
Inflammatory mechansims in pulmonary sarcoidosis
(1997-05-09)
years. We also found a positive association between DR15(2) and DR14(6) and chronic disease The strong correlations between these alleles and the outcome of the disease, indicates that the mode of antigen presentation may be of vital importance...
Depression and violence : a Swedish population study
(2016-03-10)
study, we studied a general population sample of twins (n=23,020) with continuous measures of depressive symptoms for risk of violent crime.
FINDINGS: During a mean follow-up period of 3·2 years, 641 (3·7%) of the depressed men and 152 (0...
Predictors for discontinuation of adjuvant hormone therapy in breast cancer patients
(2016-11-29)
comorbidity index (>/= 2 v 0; HR, 1.35; 95% CI, 1.03 to 1.76); and use of analgesics (HR, 1.33; 95% CI, 1.16 to 1.52), hypnotics/sedatives (HR, 1.24; 95% CI, 1.07 to 1.43), GI drugs (HR, 1.25; 95% CI, 1.08 to 1.43), and hormone replacement therapy (HR, 1...