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The Influence of Maternal Depression during Pregnancy on Neonatal Fiber Tract Integrity
(2016-12-13)
Introduction: Prenatal maternal depression is a common complication and has been associated with poor mental health outcomes and altered brain structure in the child. Neurobiological mechanisms mediating these outcomes ...
Exploring the therapeutic effects of p53 modulation in cancer and immune cell biology
(2023-04-26)
The tumor suppressor protein p53 is dysregulated in almost all cancer. In around 50% of cancer p53 retains wild type activity but its inactivation by the E3 ligase MDM2 in a heterodimer complex with MDMX may be amplified, ...
Tuberculosis and HIV : evaluation of new tests for diagnostic accuracy, cost-effectiveness and effect on treatment of tuberculosis in Smear-Negative HIV-positive patients in Uganda
(2015-04-29)
Background: Despite tremendous progress in the control of the global tuberculosis (TB) epidemic during the past decade, it is
still a major health problem even today. The burden of TB is particularly severe in sub-Sahara ...
Interplay between birthweight, family history, obesity, and genes in the development of latent autoimmune diabetes in adults (LADA) and type 2 diabetes
(2019-08-07)
Diabetes is a chronic and serious public health concern affecting millions of people around the globe. For effective prevention understanding of modifiable risk factors is fundamental. For type 2 diabetes these risk factors ...
Studies of immune response in human tuberculosis
(2013-11-21)
TB (tuberculosis), caused by Mycobacterium tuberculosis (Mtb), continues to be a world-leading killer and a serious global health problem primarily affecting poor people in many developing countries. The difficult situation ...