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Regulation of Hedgehog signalling during development and carcinogenesis
(2009-11-26)
Hedgehog (Hh) signalling is one of the most important signalling networks in the body and, when miss-regulated, has been implicated in many human tumours, particularly that of skin (Basal Cell Carcinoma, BCC) and brain ...
A 'new public health' perspective on building competence for end-of-life care and communication : how death literacy can be developed and measured
(2022-08-19)
Background: Due to aging populations and prolonged dying trajectories in many high-income countries including Sweden, more people will need extended periods of care and support at the end-of-life (EOL). In light of these ...
Genetics of primary immunodeficiency diseases
(2009-10-15)
Selective IgA deficiency (IgAD) (serum IgA concentration of <0.07 g/l) is the most common primary immunodeficiency in Caucasians, with an estimated prevalence of 1/600. There are strong indications for involvement of genetic ...
High dose rate brachytherapy boost for localized prostate cancer : clinical and patient-reported outcomes
(2006-11-17)
Curative treatment of prostate cancer is controversial. The therapeutic effects of surgery and radiotherapy (RT) have hitherto proved to be similar, why other endpoints such as health related quality of life (HRQoL) stay ...