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Non-coding RNA-based therapeutics and biomarkers for treatment and detection of vascular disease
(2021-12-23)
Cardiovascular disease (CVD), with atherosclerosis as its main underlying pathology, is the most prominent cause of death worldwide. Progression and rupture of atherosclerotic plaques lead to potential adverse pathological ...
Toxicity of brominated flame retardants with focus on retinoid system disturbances
(2015-05-18)
Background: Brominated flame retardants (BFR) are detected in the environment and biota all over the world. They contribute to the human body burden of industrial chemicals and exposure is mainly via food. Indoor dust ...
DNA repair by HDR in experimental tumorigenesis
(2008-05-15)
The aim of this thesis was to further understand how defects in the homology-directed repair (HDR) pathway affect tumor formation and development. To study proteins involved in HDR is challenging since most of its members ...