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Analysis of basic motor behaviors in quadrupeds
(2020-01-30)
Ability to perform locomotion in different directions and maintain upright body posture is crucial for normal life. At present, mice, which allows employing genetic approaches, are widely used in studying the locomotor ...
Small-molecule inhibitors of the receptor tyrosine kinases : promising tools for targeted cancer therapies
(2014-08-11)
Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of the improvements in the life quality of patients, their effectiveness is compromised by several disadvantages. This represents a ...
Targeting chronic lymphocytic leukemia cells using anti-ROR1 monoclonal antibodies and small molecules inhibitors
(2015-04-29)
Chronic lymphocytic leukemia (CLL) is characterized by accumulation of malignant B cells in blood,
bone marrow, spleen and lymph nodes. It is the most common leukemia in the Western world. Major
progress has been made ...