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Clinical, microbiological and immunological effects of antiseptics in periodontal treatment
(2019-12-19)
Periodontal diseases are characterized by high prevalence in many populations and the chronic and progressive course of the disease. A fundamental stage of treatment is mechanical debridement of the tooth surface. During ...
Prevention of growth failure caused by glucocorticoids and inflammation
(2019-10-24)
Longitudinal bone growth is a complex process that takes place in the growth plate, and normal growth is dependent on a precise balance of several endocrine and paracrine factors. Growth impairment is common in children ...
Novel aspects of metabolic regulation and inflammation in human adipocytes
(2015-04-28)
The significance of adipose tissue and obesity has been recognized in numerous pathologies. However, the mechanisms behind this connection are not yet completely understood. The aim of this thesis was to investigate the ...
Prevention of growth failure caused by glucocorticoid treatment
(2023-03-10)
Children with chronic inflammation often suffer from growth failure and many of these children are treated with high doses of glucocorticoids (GCs). However, the underlying mechanisms of growth failure under conditions of ...
Kinase cascades in the regulation of glucose homeostasis
(2005-03-09)
Therapeutic strategies to treat Type 2 Diabetes Mellitus (T2DM) aim at
improving muscle insulin sensitivity by either directly modulating, or
bypassing defective insulin signaling. Insulin induces metabolic and ...