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Quality of life, physical activity and bone health in idiopathic scoliosis
(2019-04-16)
Idiopathic scoliosis is a deformation of the spine affecting 1-3% of children and adolescents during growth. Severe deformities may lead to pulmonary dysfunction, pain and decreased quality of life. The etiology of the ...
Influence of genetic polymorphisms on DNA repair, p53 mutations and cancer risk
(2006-09-29)
Individuals have different susceptibility towards environmental exposures that may cause or contribute to disease. This inter-individual variation is partly due to genetic polymorphisms in genes involved in DNA repair and ...
Developmental role and ligand binding properties of macrophage scavenger receptor MARCO
(2006-08-11)
Macrophages express several cell surface receptors, that mediate the recognition of a wide range of endogenous and exogenous ligands. In this manner, macrophages are able to perform their multiple biological functions in ...
Molecular characterization of apoptosis in B-cell chronic lymphocytic leukemia
(2005-03-18)
B-cell chronic lymphocytic leukemia (B-CLL), characterized by an accumulation of monclonal B cells, is the most common adult leukemia in the Western world. Defective apoptosis is considered to contribute to cell accumulation, ...