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Role of GPS2 in epigenome alterations linked to metaflammation
(2018-10-18)
Current evidence suggests that transcriptional and epigenomic reprogramming events, triggered by transcription factors and chromatin-modifying co-regulators, are of central importance for disease development. G-protein ...
Antibiotic resistance in Gram-negative bacilli : with focus on cephalosporin resistance mechanisms in Escherichia coli and Klebsiella pneumoniae
(2008-09-26)
Objectives: The objectives of this thesis were to study mechanisms
conferring cefuroxime resistance in clinical non-ESBL (extended-spectrum
beta-lactamase) producing isolates of Escherichia coli and Klebsiella
pneumoniae, ...
Pulmonary manifestations in smoking-related diseases : clinical studies with emphasis on chronic obstructive pulmonary disease and rheumatoid arthritis
(2014-10-03)
Smoking is a risk factor for a number of diseases including chronic obstructive
pulmonary disease (COPD) and rheumatoid arthritis (RA). Cigarette smoke initiates
an inflammatory response which leads to structural changes ...
Cat allergy : diagnosis and characterization of important allergens
(2008-05-09)
Allergy affects about 25% of the population. Allergic diseases are
manifested in many ways, from mild rhinitis to life-threatening
anaphylaxis. Globally, more than 15% of children and adults are allergic
to pets.
The ...
Platelet angiogenic activities and their regulation on endothelial progenitor cell functions
(2015-08-12)
Platelets are essential for haemostasis and thrombosis, but also play a major role in angiogenesis. Activated platelets recruit progenitor cells and induce differentiation into endothelial progenitor cells (EPCs), which ...
C/EBP transcription factors in lung cellular differentiation and development
(2005-11-25)
During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute ...
Immunopathogenesis in pulmonary tuberculosis : impact of immunomodulation and diabetes co-morbidity
(2021-02-26)
Even in the 21st century, tuberculosis (TB) remains a major global health threat, primarily due to the emergence of antibiotic resistance. Presence of co-morbidities such as diabetes mellitus (DM) has worsened the current ...
Occurrence of human papillomaviruses (HPV) types in HPV related cancer and in the genital and oral tracts of young adults
(2012-08-24)
Human papillomavirus (HPV) is associated to cancer of the uterine cervix, the third most common
cancer among women, but also to head and neck squamous cell carcinoma (HNSCC), the sixth most
common type of cancer in the ...