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Bile acid metabolism in humans : regulation of synthesis and circadian rhythms
(2018-10-03)
Interfering with bile acids (BAs) signaling within the enterohepatic circulation (EHC) has recently emerged as an important way of controlling human metabolic homeostasis. This is highly relevant to a number of frequent ...
Epithelial stem cells in Hutchinson-Gilford progeria syndrome
(2015-01-07)
Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) are two rare
genetic disorders that affect children. Complications from cardiovascular disease, including
atherosclerosis, are the most common ...
TGF-β affects the differentiation of human GM-CSF+ CD4+ T cells in an activation- and sodium-dependent manner
(2017-05-24)
The cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) is involved in
the pathogenesis of chronic inflammatory diseases such as multiple sclerosis. However,
the environmental cues promoting differentiation ...