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Dysfunctional phenotype of T cells and their contribution to impaired B cell function during HIV-1 infection
(2016-08-29)
Microbial translocation and increased immune activation have been involved in functional T cell impairments and disease progression during HIV-1 infection. The impact of microbial translocation on the phenotype of memory ...
Lumbar fusion for chronic low-back pain in isthmic spondylolisthesis
(2008-11-21)
Manifestation of isthmic spondylolisthesis (IS), with a prevalence of 5% in the general population, varies from totally asymptomatic to severe disability. Although fusion has positive short-term effects, the long-term ...
Definition of immunoglobulin germline genes by next generation sequencing for studies of antigen-specific B cell responses
(2019-11-21)
Immunoglobulins play a critical role in the adaptive immune system, existing as cell surface-expressed B cell receptors and secreted antibodies. Circulating antibodies are the main correlate of protective immunity for most ...