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Ephrin and Eph-receptor growth factor signaling in non small cell lung cancer : identification of biomarkers and therapeutic targets
(2016-04-29)
Non-small cell lung cancer (NSCLC) is the main subtype of lung cancer (LC) and unfortunately it responds very poorly to conventional chemo- and radiotherapy (RT). Moreover, NSCLC is often diagnosed at a stage where metastases ...
Improved scientific basis for human health risk assessment factors by toxicokinetic population modeling
(2013-08-12)
Exposure limits or guidelines are derived to protect humans from adverse effects caused by exposure to chemical substances in the environment or at the workplace. The internal dose of a chemical is determined by toxicokinetic ...
Risk indicators for esophageal cancer : some medical conditions and tobacco-related indicators
(2007-05-14)
Because of little progress in the prognosis and survival of esophageal
cancer patients, the early diagnosis and prevention have been
prioritized. Alcohol consumption and tobacco smoking are the main risk
factors of ...
Cochlear implantation : experimental and clinical studies
(2016-11-18)
Cochlear implantation makes hearing restoration possible in patients with severe to profound hearing loss. However, patients with residual hearing, where a cochlear implant may be combined with acoustic stimulation, and ...