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Structural and functional studies on glutaredoxins and members of the thioredoxin superfamily
(2008-12-19)
The active site of E.coli glutaredoxin 3 was investigated using a combination of experimental and theoretical techniques. Starting from different conformations, molecular dynamics simulations converged to an active site ...
Asthmatics as a susceptible population in health risk assessment of airborne chemicals
(2016-01-20)
Asthma is a common chronic airway disease and about 235-300 million individuals of all
ages are affected by the disease around the world. A precondition of asthma has been
suggested to increase individual susceptibility ...
Systems microscopy analysis of cell migration
(2015-11-18)
Single cell migration is heterogeneous and a complicated process. It arises from a hugely complex network of multi-scale interactions between molecular and macromolecular entities. Though the full, spatiotemporally resolved ...
Preventive home visits among older people : risk assessment, self-rated health and experiences of healthy ageing
(2021-04-07)
Background: The worldwide population is ageing and life expectancy is increasing. This increase in age is associated with physiological and psychosocial challenges and changes that lead to decreased intrinsic capacity and ...
Delivering health services to children through integrated community case management in Uganda : from innovation to institutionalisation
(2014-09-23)
Background: Infectious diseases cause the majority of childhood deaths in low income settings. Integrated community case management (iCCM) is a health innovation relying on community health workers (CHWs) to diagnose and ...
Application of the benchmark dose-response modelling approach for risk characterization of chemicals
(2022-04-28)
Toxicology is the discipline that investigates the possible adverse effects of chemical exposure on human, animal and environmental health. Chemical risk assessment is the process that aims to identify potentially hazardous ...