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Misoprostol : pharmacokinetics and effects on uterine contractility and cervical ripening in early pregnancy
(2007-08-17)
Misoprostol is an orally active synthetic PGE1 analogue which has become
an important drug in obstetric and gynaecological practice because of its
uterotonic and cervical priming actions. It is safe, cheap, widely
available ...
Long-term exposure to air pollution from road traffic and cardiovascular disease with a focus on exposure modeling
(2015-11-20)
Air pollution is an important environmental health factor contributing to the burden of disease. From a public health point of view cardiovascular effects of long-term exposure are predominant, primarily coronary events ...
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
(Nature Publishing group, 2022-08-18)
Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements. Aberrant Ca2+ handling is a key feature of HF pathophysiology. ...