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HMGB1 : regulation of inflammatory functions and therapeutic blockade
(2015-04-01)
The intracellular protein High Mobility Group Box Protein 1 (HMGB1) has been
identified as a pivotal mediator of inflammation. HMGB1 can be released by various
mechanisms and as an inflammatory mediator it induces both ...
Genetic and functional analyses of diabetic nephropathy with focus on chromosome 3q
(2010-05-14)
Diabetic nephropathy (DN) is a complex disease affected by both genetic and environmental factors. Genetic and functional analyses of the susceptibility and/or resistance genes in DN may provide useful information for ...
T-cell specificity and regulation in atherosclerosis
(2015-12-14)
Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived ...