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Mechanisms of immune dysfunction in human lymphomas
(1999-11-26)
Accumulating data suggest that tumor-induced immune dysfunction counteracts presumptively efficient tumor-specific immune responses, and thus contributes to disease progression. In the present work, focus was given on ...
Oral graft versus host disease : salivary gland pathology and tissue modelling
(2024-04-04)
Chronic Graft versus Host Disease (cGVHD) is a consequence of dysregulated immune
reconstitution after allogenic hematopoietic cell transplantation (alloHCT), a treatment for
high-risk blood malignancies or immune ...
Home-cage monitoring of mouse behaviours across life-span
(2019-04-25)
Background and aim: The academic research involving animal testing is struggling with problems of reproducibility and a few of the specific reasons pointed out are for example insufficient reporting of animal strains and ...
Clinical studies of CYP3A4 and P-glycoprotein
(2016-10-12)
In the field of pharmacokinetics, cytochrome P450 enzymes have been extensively studied. The CYP450 enzyme with the most drug substrates is CYP3A4, but despite its significance, administration of a specific substrate to ...
Immunoreactive proteins in Taenia solium/cysticercus cellulosae
(2016-03-17)
Cysticercosis caused by Taenia solium is a common zoonotic parasitic disease in Latin America, Asia, Africa, and parts of Oceania, and it is responsible for many cases of epileptic seizures. Imaging techniques used to ...
The importance of thyroid function for female reproduction
(2019-02-18)
Background: Thyroid dysfunction is one of the most common endocrine disorder. Thyroid dysfunction affects the female reproductive system and can be manifested by menstrual irregularities, pregnancy loss and infertility. ...
Increasing access to abortion : perspectives on provider availability from different settings
(2016-12-15)
Background: Unsafe abortion is estimated to cause around 23000 maternal deaths yearly, most of those deaths are preventable by proper use of contraception and access to safe abortion. Barriers to access to safe abortion ...
Physical activity, body composition, inflammation and effects on antioxidative capacity in sedentary adults
(2016-08-05)
Background: For the past fifty years part the population has slowly become sedentary to an
extent that it is nowadays considered normal behavior. Parallel with sedentary behavior there
is an increase in obesity now ...
Living with osteogenesis imperfecta
(2015-09-17)
Osteogenesis Imperfecta (OI) is a hereditary connective tissue disorder with fragility of the bones as the dominant symptom. There is no cure for OI, but symptoms are treated with medical, orthopaedic and physiotherapy ...
Sense of coherence (SOC) in women treated for breast cancer and its relation to treatment outcome
(2016-04-20)
Breast cancer incidence has, on average increased by 1.4 % annually during the last decades. Early detection and advances in treatment are the main contributing factors for the favourable outcome in terms of five- and ...