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From optic neuritis to multiple sclerosis : a paraclinical, epidemiological, and etiological study in Stockholm County, Sweden
(1999-10-22)
The etiology of multiple sclerosis (MS) is unknown. Monosymptomatic optic neuritis (MON) is an acute disease of the optic nerve attributed to focal inflammation associated with demyelination in the absence of any history ...
Role of syntaxin-11 and munc18-2 in lymphocyte cytotoxic granule exocytosis
(2016-08-18)
Mutations in genes required for the exocytosis of cytotoxic granules by NK cells and cytotoxic T lymphocytes are associated with early-onset familial hemophagocytic lymphohistiocytosis (FHL). In this project, we examined ...
Interactions between neuroblastoma and the immune system : cellular pathways and mediators
(2011-03-04)
Neuroblastoma (NB) is an embryonal tumor of early childhood arising in tissues of the sympathetic nervous system, such as the adrenal gland and paraspinal ganglia. It is the most common extra-cranial solid tumor of childhood, ...