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Type IV collagen : regulation of COL4A1 and COL4A2 genes and gene therapy of Alport syndrome
(1999-05-07)
Type IV collagen is an important structural protein in basement membranes, which am thin sheet-like structures located between organized tissues and the connective tissue. Type IV collagen is composed of six genetically ...
Telephone advice nursing : callers’ perceptions, nurses’ experience of problems and basis for assessments
(2004-01-02)
At a health care call center, care-seekers can consult telephone nurses 24 hours a day. Telephone advice nursing (TAN) includes triage, advice, support, education, referral, information and coordination. The overall aim ...
Physical activity in rheumatoid arthritis
(2006-04-28)
Physical activity confers health benefits in the general population and should also be applied to people with rheumatoid arthritis (RA). However, there is a need for more research in this area. The aim of this thesis was ...
Conformational dynamics in microRNAs : the example of miR-34a targeting Sirt1 mRNA
(2020-06-17)
In biology, regulatory mechanisms are essential to achieve complex tasks, as virtually every process can be positively or negatively modulated in its outcome, upon different cues. In humans, microRNAs (miRNAs) constitute ...
Single-cell analysis of mammalian cardiogenesis elucidating an essential role of outflow tract progenitors
(2021-09-14)
The heart is the first organ to form and start to function during mammalian embryogenesis. This complex organ system is constructed by a diverse set of cell types, involving mesodermal precursors and heart progenitors, at ...
The relation among aging, dopamine-regulating genes, and neurocognition
(2020-10-07)
When people are getting old, they often feel increasingly harder to concentrate, and become slower and more inflexible during tasks that involve focused attention, information maintenance in the face of distractions, and ...
Outcome after allogeneic stem cell transplantation with special reference to non-malignant disorders, chimerism and graft cell composition
(2018-10-03)
The outcome for patients undergoing allogeneic stem cell transplantation (HSCT), a treatment for several severe malignant and non-malignant disorders with hematopoietic origin, is a balancing act between beneficiary effects ...