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Pharmacodynamic interactions of quinolines with other antimalarial compounds in vitro
(2005-05-03)
Chemotherapy remains the most reliable means for the control of Plasmodium falciparum malaria. Unfortunately the parasite has been able to develop resistance to the majority of the antimalarials currently employed.
Success ...
Nephroprotective effect of the cardiotonic steroid ouabain
(2014-04-30)
It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA. Exposure of renal cells to low concentrations of the highly specific ...
Regulation of non-responsiveness and death in cytotoxic T cells by the agonistic potency of MHC : peptide ligands
(2006-04-21)
CD8+ T lymphocytes are important for immunological control of infections and tumors. The key interaction required to initiate the process of T cell activation is the engagement of the T cell receptor (TCR) with a major ...