Search
Now showing items 1-10 of 17
Genetic studies of familial hemophagocytic lymphohistiocytosis
(2004-11-05)
The main contribution from this thesis is a refined knowledge of locus heterogeneity in familial hernophagocytic lympbohistiocytosis (FHL) and a further characterization of corresponding clinical and immunological ...
Improving quality of life using mind-body therapies : the evaluation of a course intervention for personal self-awareness and development
(2009-02-19)
The general aim of this research project was to conduct a research
project in complementary alternative medicine (CAM), and to evaluate an
unusual course method. Since 1985 a special training centre, founded by
Bengt ...
Ah receptor mediated toxicity : studies in vitro and in a transgenic mouse model
(2007-02-01)
The polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls are ubiquitously present in the environment. Humans are exposed mainly through diet to continuous low levels which on average are in close proximity to ...
Assessment of cognitive function in elderly patients with hip fractures
(2007-03-09)
Impaired cognitive function is common among elderly patients. The aim of this thesis was to illuminate the documentation of cognitive function in elderly patients with hip fractures and to study the effect of cognitive ...
Tartrate resistant acid phosphatase 5a : a potential regulator of adipocyte cell number and differentiation in white adipose tissue
(2015-04-02)
Tartrate-resistant acid phosphatase (TRAP) exists in two isoforms, TRAP 5a which is monomeric and TRAP 5b which is a dimer generated by proteolytic cleavage of TRAP 5a, that exhibit different functions and localizations. ...
Hip fracture in young and old subjects : aspects on risk factors and outcome
(2011-11-18)
Hip fractures, the most serious osteoporosis-related fractures, mainly affect older people. The functional outcome for many hip fracture patients remains to be improved. Hip fractures in young patients are uncommon, but ...
Mitochondria : a target for anticancer therapy
(2014-12-17)
Mitochondria possess a central role in several cellular metabolic pathways, maintenance of calcium homeostasis, production of reactive oxygen species (ROS) and in the regulation of various cell death modalities. A majority ...
Wrist fractures : aspects of surgical methods and outcome
(2014-05-23)
Wrist fractures are the most frequently occurring fractures in any emergency setting. Treatment
regimens range from a plaster cast to a combination of advanced surgical methods. Many fractures
heal without remaining ...
Exploring the potential of antiangiogenic strategies targeting the TGF-β family in the tumor microenvironment
(2012-11-01)
Members of the transforming growth factor (TGF)-β family exert their effect on virtually all cell types in the body, producing diverse and complex cellular responses. Additionally, TGF-β signaling is deregulated and ...
PCR adjusted cure rates in clinical trials of antimalarial drugs in Africa : influence of extended follow-up and consecutive day blood sampling
(2008-10-25)
Malaria treatment guidelines are based primarily on results from clinical
trials. Accurate assessment of drug efficacy in such studies therefore
represents a prerequisite to ensure effective and lifesaving treatment
for ...